Metastatic Androgen-Independent Prostate Cancer (mAIPC)
mAIPC is a rapidly progressing stage of prostate cancer. It leads to a marked deterioration
in the quality of life, and most patients with prostate cancer die during this stage.1,2
There is a lack of consensus on the definition of mAIPC, but this stage may be characterized
by confirmed metastases in the presence of castrate serum levels of testosterone
(≤50 ng/mL) or rising PSA.3
Learn more about prostate cancer:
1. Scher HI, Leibel SA, Fuks Z, Cordon-Cardo C, Scardino PT. Cancer of the prostate.
In: DeVita VT, Hellman S, Rosenberger SA, eds. Cancer: Principles & Practice
of Oncology. 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005:1192-1259.
2. Pound CR, Partin AW, Eisenberger MA, Chan DW, Pearson JD, Walsh PC. Natural history
of progression after PSA elevation following radical prostatectomy. JAMA. 1999;281(17):1591-1597.
3. Martel CL, Gumerlock PH, Meyers FJ, Lara PN. Current strategies in the management
of hormone-refractory prostate cancer. Cancer Treat Rev. 2003;29(3):171-187.